CORDOMA DEL CLIVUS PDF

CORDOMA DEL CLIVUS PDF

con el diagnóstico histopatológico de cordoma de la base del cráneo .. magnética cerebral, corte sagital, secuencia T1, cordoma del clivus. Resección endoscópica de cordoma del clivus. Descripción de un chordoma; clivus; endoscopic resection; malignant tumor. RESUMEN. Download Citation on ResearchGate | On Dec 19, , Ines Gamboa and others published Resección endoscópica de cordoma del clivus. Descripción de un.

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Examination Physical examination was unremarkable aside from a finding of tenderness over the right sacroiliac joint and a mildly diminished deep-tendon reflex at the right cordomz. Those located in the spheno-occipital region most commonly occur in patients years of age, whereas sacrococcygeal chordomas are typically seen in a slightly older age group peak around 50 years Xel Journal of Cancer.

In the first consensus guidelines for the diagnosis and treatment of chordoma were published in the Lancet Oncology. We chose the retromastoid suboccipital approach.

Intradural retroclival chordoma without bone involvement: Not to be confused with Chondroma. A developmental lesion related to chordoma is the ecchordosis physaliphora. Sitting, especially driving, aggravated the pain, whereas standing and lumbar hyperextension provided some relief. Intradural cordo,a are extremely rare and, although they resemble classic chordomas in terms of both their notochordal origin and microscopic features, they are clinicopathologically distinct.

Examination On initial evaluation, the patient had ataxic gait. The role of radiosurgery in the management of chordoma and chondrosarcoma of the cranial base.

Find articles by Seung Jin Noh. Microscopically, chordomas are characterised by physaliphorous cells. The yellow-brown spherical tumor was situated between the scalloped pedicle of the L-3 vertebra and nerve root.

Extraosseous spinal chordoma

A small number of families have been reported in which multiple relatives have been affected by chordoma. Such tumors often showed extraosseous extensions that were out of proportion to the degree of osseous involvement and were most often anterior and lateral but did involve the posterior spinal area.

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Photomicrograph of the intradural tumor showing typical physaliphorous cells in mucinous matrix. Axial contrast enhanced brain CT image.

Her magnetic resonance images demonstrated an inhomogeneously contrast-enhanced large tumor growing into right cavernous sinus and Meckel’s cave located totally within intradural retroclival region. The disc protrusion at the L-2 interspace was considered clinically significant in that it explained the presence of pain in the right thigh.

Open in a separate window. Based on our morphological and immunohistochemical studies, we propose that the tumor presented in this report, a bona fide intraspinal extraosseous extradural chordoma, had its origin in an ectopic notochordal remnant.

Extraosseous spinal chordoma in: Journal of Neurosurgery Volume 75 Issue 6 Year

Plain radiographs of the lumbar spine did not demonstrate a destructive lesion, either lytic or blastic both of which are typical of chordomas.

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Cordo,a entities show different biological behavior, with gradient evolution of growth and malignancy from the usually asymptomatic ecchordosis, to the slowly evolving intradural chordoma, to the highly malignant and invasive chordoma Some advocate the combination of radiation therapy and complete or subtotal surgical resection for select patients 6.

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Intradural Retroclival Chordoma

We achieved near total resection of intradural chordoma and adjuvant gamma knife radiosurgery was performed for remnant tumor at 1 month after surgery. Chordomas can arise from bone in the skull base and anywhere along the spine. xel

This neoplasm is thought to be essentially extradural in nature and generally associated with extradural extension corsoma bone destruction. The remainder of the neurological examination was within normal ranges. The patient was not aware of progressive neurological loss. However, stereotactic radiosurgery is valuable as an adjuvant or primary treatment for selected patients with chordoma and has potential advantages over standard fractionated irradiation, although the length of follow-up review has been insufficient 7.

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These tumours are often poorly marginated and microscopic distal extension of tumor cells likely explains the frequency of recurrences. Author information Article notes Copyright and License information Disclaimer. Histological, immunocytochemical, and ultrastructural studies confirmed the diagnosis of chordoma Figs.

Benign bone erosion with sclerotic borders can be seen arrowindicating a long-standing erosive, rather than destructive, process.

Although this tumor lends itself to complete removal, long-term follow-up monitoring is needed to determine the possibility of recurrence. This herniation was not evident on the magnetic resonance imaging despite axial sections through this interspace.

Sagittal Gd-enhanced T1-weighted image. Check for errors and try again. Although the histological, immunocytochemical, and ultrastructural features of this tumor are those of ordinary cranial, dfl, or sacral chordoma, the tumor described in this report exhibits a different topography and growth pattern, being extraosseous and confined to the epidural space.

Related Radiopaedia articles Bone tumours The differential diagnosis for bone tumours is dependent on the age of the patient, with a very different set of differentials for the pediatric patient. There are currently no known environmental risk factors for chordoma.